AMV Hospitals

Puppalaguda

+91 - 9100009669

Attapur

+91 - 8008842200

Book Appointment

Attapur

+91 - 8008842200

Puppalaguda

+91 - 9100009669
Book Appointment

Physiological Intracytoplasmic Sperm Injection(PICSI) Treatment in Hyderabad

Years of Experience
0 +
Successful Surgeries
0 +
Happy Families
0 +

What is PICSI

PICSI, or Physiological Intracytoplasmic Sperm Injection, is an advanced fertility treatment designed to improve IVF success by selecting healthier and more mature sperm. This technique closely mimics the natural fertilization process by allowing sperm to bind to hyaluronan, a substance naturally found around the human egg in the female reproductive system.

Unlike standard ICSI, where sperm selection is mainly based on appearance and movement under a microscope, PICSI focuses on the biological maturity and DNA integrity of the sperm. Only sperm capable of binding to hyaluronan are chosen, increasing the chances of successful fertilization and healthy embryo development.

PICSI

Principle of the PICSI Method

  • Hyaluronic acid is a natural component of the egg’s outer layer.
  • Only mature sperm have receptors that allow them to bind to hyaluronic acid.
  • This binding process occurs naturally during fertilization.
  • In PICSI, sperm are placed in a hyaluronic acid–coated dish.
  • abnormalities.
  • Sperm that successfully bind are selected for fertilization.
  • The selected sperm are injected into the egg using the ICSI technique.
  • Hyaluronic acid–bound sperm show better morphology, stronger DNA integrity, and fewer chromosomal

When IVF doesn’t succeed, what are the next steps?

PICSI is recommended for couples who need advanced sperm selection to improve fertilization outcomes, including

High sperm DNA fragmentation (high DFI)

In Vitro Fertilization in Hyderabad

Women above 38 years of age

In Vitro Fertilization in Hyderabad

Previous failed ICSI cycles

Poor embryo quality

In Vitro Fertilization in Hyderabad

History of recurrent miscarriages

In Vitro Fertilization in Hyderabad

Male factor infertility with low sperm quality

At AMVI Hospital, Hyderabad, our fertility specialists offer personalized PICSI treatment at our Attapur and Puppalaguda centers.

How Is PICSI Performed?

A special dish coated with hyaluronan—similar to the natural layer surrounding the egg—is prepared. Ready-to-use PICSI dishes are commonly used in modern laboratories.

A semen sample is collected from the male partner and processed to separate healthy sperm from other components.

The prepared sperm sample is placed on the hyaluronan-coated dish. Only mature and functionally healthy sperm bind to the surface.

Under a microscope, the sperm attached to the hyaluronan are identified as high-quality sperm.

The selected sperm are then individually injected into the egg using the ICSI technique to achieve fertilization.

PICSI
About doctor

Dr Shaivalini Kamarapu – PICSI & Fertility Specialist

Gynecologist, Fertility Specialist, Robotics & Laparoscopy Surgeon

About Dr Shaivalini Kamarapu (PICSI Specialist)
  • Dr. Shaivalini Kamarapu is a highly experienced IVF and infertility specialist with over 20 years of expertise in women’s reproductive health.
  • She specializes in advanced IVF techniques, including PICSI, offering personalized and evidence-based fertility treatment.
  • Her clinical expertise includes PICSI, IVF, IUI, ovulation induction, and fertility preservation.
  • She has extensive experience managing complex infertility cases, particularly male factor infertility and repeated IVF failure.
  • Dr. Kamarapu follows a patient-centric and ethical approach, ensuring transparent counselling and customized treatment plans.
  • She works with advanced embryology techniques to improve fertilizations rates and overall IVF success.
  • Consultant at Rainbow, Apollo & Ankura Hospitals.
Book Appointment

How Is PICSI Performed?

  • Poor overall sperm quality
  • Low sperm motility (reduced movement)
  • Abnormal sperm shape or structure (morphology issues)
  • High sperm DNA fragmentation levels
  • Previous IVF or ICSI failures linked to male factor infertility
  • Need for improved fertilization and embryo development outcomes

How Does PICSI Influence IVF Success Rates?

PICSI plays an important role in improving IVF outcomes by enhancing sperm selection and embryo quality. Clinical evidence shows higher pregnancy rates and a reduced risk of miscarriage in IVF cycles using PICSI. By choosing sperm with intact DNA and strong fertilizing ability, PICSI increases the chances of successful assisted reproductive treatment.

Why choose Amvi hospital For PICSI treatment

Experienced & Trusted Medical Specialists

In Vitro Fertilization in Hyderabad

Advanced Multispecialty Healthcare Services

In Vitro Fertilization in Hyderabad

State-of-the-Art
Medical Technology

In Vitro Fertilization in Hyderabad

Comprehensive Care
Under One Roof

In Vitro Fertilization in Hyderabad

Personalised Treatment Plans for Every Patient

In Vitro Fertilization in Hyderabad

Patient-First Treatment Approach

In Vitro Fertilization in Hyderabad

Comfortable Hospital Infrastructure & Facilities

In Vitro Fertilization in Hyderabad

Dedicated Support Staff & Patient Care Team

Trusted Hospital for Quality Healthcare Services

Book Appointment

Our PICSI treatment centers in Hyderabad

Puppalaguda

  • Hallmark Empyrean Commercial Complex Narsingi-Puppalaguda Main Road Puppalaguda, Puppalaguda - Manikonda Main Rd, opposite to Sloka school, Hyderabad, Telangana 500089
  • 91-91000 09669
  • amvihospitals@gmail.com

Attapur

Testimonials

We chose PICSI treatment at AMVI Maternity & Fertility Hospital, Attapur, and the experience was very reassuring. The doctor explained the process clearly and guided us with patience.

Anjali R

Our PICSI treatment at AMVI Hospital, Puppalguda, was handled with great care. The counselling was transparent and tailored to our needs.

Suresh & Kavya M

During my PICSI treatment at AMVI Hospital in Attapur, I felt well supported. Every step was explained in a calm and professional manner.

Neha P.

After a previous IVF failure, we opted for PICSI treatment at AMVI Hospital, Puppalguda. The personalized approach gave us renewed confidence.

Rahul & Sneha K

The PICSI treatment experience at AMVI Hospital, Attapur, was smooth and well organized. The team patiently answered all our questions.

Pooja S

Our blogs related to PICSI

An Innovative Step in Women’s Intimate Wellness With O-Shot Treatment

Endometriosis Diet that Nourish Your Body for Better Health & Fertility

Cosmetic Gynecology with Restoring Confidence, Comfort, and Intimate Wellness

FAQs related to PICSI

Research and clinical findings show that PICSI can enhance embryo quality and improve pregnancy outcomes by selecting sperm with higher maturity and better genetic stability, particularly in male infertility cases.

Yes, PICSI is considered a safe and reliable laboratory procedure. It follows the same steps as ICSI, with an additional sperm selection method, and does not pose extra risk to the egg or embryo.

  • IVF: Fertilization occurs naturally by placing eggs and sperm together in a lab dish.
  • ICSI: One sperm is injected directly into the egg.
  • PICSI: An advanced version of ICSI where sperm are first selected based on natural binding ability, indicating better quality.

The cost of PICSI depends on individual treatment plans and whether it is used alongside IVF or ICSI. At AMVI Hospital, detailed cost information is shared during the fertility consultation.

Yes, PICSI is helpful in cases with high DNA fragmentation as it allows embryologists to choose sperm with intact genetic material.

The sperm selection for PICSI is completed on the same day as egg retrieval and fertilization and does not significantly extend the treatment timeline.

PICSI does not introduce additional risks beyond those associated with standard ICSI and is safe when performed by trained fertility specialists.

Yes, PICSI is often combined with IVF or ICSI and can be part of a comprehensive fertility treatment plan based on medical advice.

Healthy habits such as balanced nutrition, regular exercise, avoiding tobacco and alcohol, managing stress, and following medical guidance can positively influence treatment success.

You can consult AMVI Fertility & Maternity Care at our Hyderabad locations in Attapur and Puppalaguda, where experienced fertility specialists provide compassionate, advanced care for PICSI failure and infertility.

After PICSI, embryos are monitored for growth and development. Embryo transfer and pregnancy testing are planned, followed by ongoing care and follow-up at AMVI Hospital.

Looking for Expert Medical Care? Book an Appointment Today!