AMV Hospitals

Intracytoplasmic Sperm Injection (ICSI) - Male Infertility Treatment

» ICSI means Intracytoplasmic Sperm Injection

» The technique was developed by Gianpiero Palermo at Brussels University.

» The first successful birth by ICSI took place 1992

Intracytoplasmic Morphologically Selected Sperm Injection (IMSI)

IMSI is a modification of the ICSI technique where sperm samples are examined under a microscope that is almost 6000 times more powerful to better assess their “morphology”. At a higher power the embryologist can identify tiny defects in the sperm head that would not otherwise be visible with standard ICSI.

Although it is yet to be confirmed to be of benefit for all requiring sperm injection, it is recommended in those with a history of recurrent implantation failures, recurrent ICSI failures or severe teratospermia (abnormal sperm shape).

In essence it is a selection tool, to aid embryologists choose the optimal sperm for ICSI. If the sperm count or motility is already so low that it limits the number of sperm available for ICSI, IMSI may not be a suitable technique for you.

What is Intracytoplasmic morphologically selected sperm injection (IMSI)?

Intracytoplasmic morphologically selected sperm injection (IMSI) is a technique used in IVF treatment to examine and select sperm using a high-magnification digital imaging microscope for microinjection into the egg.

With the IMSI technique, our scientists are better able to assess the structure of the sperm and exclude the sperm with suspected variations from being injected into the available eggs.

Why perform IMSI?

For men with high numbers of abnormal sperm and previous poor outcomes in IVF with ICSI, an enhanced selection tool may improve likelihood of fertilization and normal embryo development.

Using digital high-magnification of sperm our scientists can examine the individual sperm at 6,000 times magnification to identify the sperm that exhibit abnormalities and exclude them from being used to fertilise the egg. The sperm that are identified as being structurally normal are then used in the fertilisation procedure using the ICSI method.

In comparison, traditional methods of selecting sperm involve our scientists assessing sperm for any visible abnormalities at 400 times magnification and selecting the most normal looking sperm to microinject into the egg.

Who is IMSI suitable for?

AMVI IVF fertility specialist may recommend IMSI if:

» you have very low numbers of sperm, and

» a high proportion of abnormally shaped sperm, 

» evidence of poor outcomes with previous ICSI treatments

How much does IMSI Cost?

Contact us to now the exact cost for the IMSI treatment. Book an appointment now and get a call back from experts.

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